Mas-Related GPCR X4 (MRGPRX4) is a sensory neuron-restricted receptor for cholestatic itch. Here, we identify MRGPRX4 as an unexpected melanoma driver. MRGPRX4 is upregulated in melanoma and is ...
The extracellular matrix is a complex network of material such as proteins and polysaccharides that are secreted locally by cells and remain closely associated with them to provide structural, ...