Markers of a new mechanism for cell death, called karyoptosis, have been found in the brains of patients with Alzheimer's ...

After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta ...

Scientists discover karyoptosis, a new cell death mechanism causing nuclear disintegration in Alzheimer's and frontotemporal ...

Histidine kinases (HK) are one of the main prokaryotic signaling systems. Two structurally conserved catalytic domains inside the HK enable autokinase, phosphotransfer, and phosphatase activities.

Protein kinase AKT plays a broad role in promoting energy production in nutrient-rich environments. However, its roles under metabolic stress remain elusive. Herein, we demonstrate a dual mechanism ...