The fragmentation of type I collagen has been seen to impair the integrity of the dermal extracellular matrix (ECM). This results in lower type I procollagen synthesis and contracted or collapsed ...

Challenging the long-standing belief that fibroblasts produce skin collagen, researchers have investigated collagen formation in the 'glass-skinned' amphibian axolotl and other vertebrates. They ...

Figure 1. (click to enlarge) Fibroblasts (blue DAPI stain) cultured on bead-like sphere structures produce embryonic ECM. Tissue engineering and regenerative medicine use various scaffolds, living ...

Please provide your email address to receive an email when new articles are posted on . Autologous dermal fibroblasts may decrease risk of rotator cuff retears after arthroscopic rotator cuff repair ...

L uis Garza, a physician-scientist at Johns Hopkins University School of Medicine for over a decade, noticed a common issue when treating people with limb amputations at his clinic. They often had ...

The skin consists of two primary layers. The epidermis, the outermost layer, is predominantly made up of keratinocytes, while ...

Axolotl is an animal model widely used in dermatology research due to its transparent ‘glass skin.’ A study by researchers from Okayama University, Japan, discovered that healthy collagen fibers, ...