Two new classifications for myeloid neoplasms were introduced in 2022: the International Consensus Classification (ICC) and the 5th edition WHO Classification (WHO-HAEM5). Both classifications build ...

The classification of AML is based on the French-American-British system in which morphologic and immunophenotypic features of blast cells divide AML into 8 distinct subtypes labeled M0-M7. M3 is the ...

Authors acknowledge that both the 2022 World Health Organization and International Consensus Classification myelodysplastic syndrome criteria sets have value, while sorting out their similarities and ...

The classification of AML and therapeutic options are now largely driven by genetically defined subtypes. Personalization of treatment relies on timely completion and reporting of cytogenetic and ...

Panelists explain that KMT2A-rearranged acute myeloid leukemia (AML) is an aggressive, molecularly distinct leukemia subtype marked by menin-dependent transcriptional dysregulation, poor response to ...