When we learn a new motor skill—whether mastering a piano passage or refining balance while walking—the brain must reorganize ...
The dopamine transporter (DAT) is integral to the regulation of synaptic dopamine levels, a process central to the maintenance of normal neurological function. DAT not only mediates the reuptake of ...
Astrocytes use the MEGF10 receptor to prune synapses in the striatum, a process essential for dopamine-driven motor learning.
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Dopamine under control: Precision regulation of inhibition shapes learning, memory and mental health
For decades, dopamine has been celebrated in neuroscience as the quintessential "reward molecule"—a chemical herald of pleasure, motivation, and reinforcement. In popular understanding, higher ...
Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the ...
This original animation illustrates that presynaptic neurons secrete VLK, which then phosphorylates the extracellular side of ephrin type-B receptor 2 (EphB2) extruding from the membranes of ...
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