Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number continues to grow rapidly. Until now, searching these vast ...
Multiple sequence alignment (MSA) is a fundamental task in bioinformatics, underpinning comparative genomics, structural analysis, and evolutionary inference. However, MSA remains a challenging ...
Sequence alignment algorithms form the foundation of comparative genomics, structural biology and evolutionary studies by identifying regions of similarity among nucleotide or protein sequences.
Researchers have unveiled LoL-align, a probabilistic protein structure alignment algorithm that outperforms TM-align and Dali ...
AMD says its ROCm-enabled MMseqs2 and HIPSW++ tools move evolutionary sequence search onto Instinct GPUs, with up to 97 TCUPS ...
Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...