Scientists have unlocked new details on important receptor proteins—promising targets for the creation of novel drugs for metabolic conditions ranging from diabetes to obesity and inflammatory ...

A single receptor in blood vessels can trigger either harmful inflammation or protective healing, but scientists have struggled to understand how this is possible. UC San Diego researchers revealed ...

New clues about the way brain chemical transmitter GABA functions suggest that a protein 'anchor' plays a key role in helping position its receptors in nervous cells. New research published in Nature ...

Researchers have identified a potential new immune checkpoint receptor that could lead to treatments for diseases such as lung and bowel cancer and autoimmune conditions including IBD. Researchers ...

The collaboration targets disease areas where conventional small molecule drug discovery has faced challenges.

Explore NMDA receptor modulation and its critical role in neuronal development and cognitive functions like learning and memory.

Taste, pain, or response to stress — nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University of ...

Receptor protein tyrosine phosphatases are cell membrane-localized proteins. They are regulators of cell–cell contacts and are also considered likely to be tumor suppressors but how they function is ...

Reinforce EP4 receptor antagonism as a validated, high-value strategy to overcome immunotherapy resistance MONTREAL and STRASBOURG, France and BOSTON, (GLOBE NEWSWIRE) -- Kainova Therapeutics (“the ...

Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, initiating cellular responses. Taste receptors, expressed in oral tissues, ...