Localizatome contains comprehensive information about the stress-induced protein localization changes within living cells. It provides open access to subcellular protein localization data through a ...

An international team has assembled the first large-scale, publicly available map to show the impact of mutations on where proteins end up in the cell. The team developed a high-throughput imaging ...

CAMBRIDGE, MA – A protein located in the wrong part of a cell can contribute to several diseases, such as Alzheimer’s, cystic fibrosis, and cancer. But there are about 70,000 different proteins and ...

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Spatial proteomics is the study of the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular function, making spatial ...

The team developed a high-throughput imaging platform to assess the influence of nearly 3,500 mutations on protein location. They found that roughly one in six disease-causing mutations led to ...

This fully updated volume explores a wide array of new and state-of-the-art tools and resources for protein function prediction. Beginning with in-depth overviews of essential underlying computational ...

Researchers created proteins that fold into logic-based shapes, letting therapies target disease sites precisely and cut off-target effects. (Nanowerk News) Targeted drug delivery is a powerful and ...