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Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...
In 2023, scientists in the joint School of Engineering and School of Life Sciences Laboratory of Protein Design and Immunoengineering (LPDI), led by Bruno Correia, published in Nature a deep-learning ...
A protein located in the wrong part of a cell can contribute to several diseases, such as Alzheimer's, cystic fibrosis, and cancer. But there are about 70,000 different proteins and protein variants ...
Morning Overview on MSN
AlphaFold rewired science, and 5 years later it’s still evolving
AlphaFold arrived as a technical moonshot that suddenly made protein structures feel like software rather than secrets of nature, and five years on it has rewired how laboratories plan experiments, ...
Scientists have used deep learning to design new proteins that bind to complexes involving other small molecules like hormones or drugs, opening up a world of possibilities in the computational design ...
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