Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap, St. Jude ...
July 13, 2026) Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap, St ...
Most cancer genome studies have focused on mutations in the tumor itself and how such gene variants allow a tumor to grow unchecked. A new study takes a deep dive into inherited cancer mutations ...
Researchers have created the first complete map showing how hundreds of mutations in a key cancer gene affect tumor growth. By testing every possible mutation in a critical hotspot, they found that ...
Many cancer-associated mutational signatures remain unexplained. Team CAUSE aims to connect DNA damage, mutational patterns, ...