In a recent study published in the IUBMB journal, researchers assessed the association between platelet-activating factor (PAF) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ...
Greinacher et al. (April 9) 1 report on the development of platelet-activating antibodies against platelet factor 4 (PF4) after ChAdOx1 nCoV-19 vaccination in patients without previous exposure to ...
Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural liver damage and improve hepatic vascular function in cirrhosis. The ...
The contractile responses of esophageal smooth muscle (SM) induced by platelet-activating factor (PAF) involve the activation of L-type voltage-dependent calcium channels (L-type VDCCs), ...
PAF causes strong contractions—especially in the muscles of the esophagus and the stomach’s upper region (called the gastric fundus). In other parts of the intestine, such as the small intestine and ...
BACKGROUND: Despite antiplatelet therapy, some patients remain at high ischemic risk because of drug nonresponsiveness or high residual platelet reactivity). We aimed to target an orphan platelet GPCR ...
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