The SOFA-2 score included new definitions, new variables, and revised thresholds to categorize the severity of organ dysfunction in critical illness. The updates reflected changes in practice, ...

Please provide your email address to receive an email when new articles are posted on . Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection.

The Journal of the American Medical Association (JAMA) has recently published the updated version of the Sequential Organ Failure Assessment (SOFA), the global reference system in intensive care ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

The Sepsis-1, Sepsis-2, and Sepsis-3 definitions are for adult sepsis. The IPCC (International Pediatric Sepsis Consensus Conference) and Phoenix definitions are for pediatric sepsis. ARDS denotes ...

Low blood pressure, or hypotension, is often overlooked because some people tolerate lower readings without obvious symptoms. However, in many situations, particularly during critical illness, trauma, ...

The sepsis definition describes three elements: infection, the host response and life-threatening organ dysfunction. Diagnosis is made based on myriad signs and symptoms, and although infection ...

Compared with placebo, a 72-hour infusion of 1 ng/kg/min iloprost does not improve outcomes or reduce the severity of organ failure among patients admitted to the intensive care unit (ICU) with septic ...

The updated version of the Sequential Organ Failure Assessment (SOFA), the global reference system in intensive care medicine used to assess the degree of organ dysfunction in critically ill patients, ...