The copy number variation (CNV) map of the human genome documents the extent and characteristics of CNV among healthy populations. Depending on the level of stringency of the map, 4.8–9.7% of the ...

When cancer spreads from a primary tumor to new sites throughout the body, it undergoes changes that increase its genetic complexity. A new study from researchers at Memorial Sloan Kettering Cancer ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

Using SNP-CGH to Profile for Amplifications, Duplications, and Deletions The beginnings of personalized medicine have been forged by recent advances in SNP genotyping technologies. It is now possible ...