AI meets cell fate: RegVelo combines RNA velocity and gene regulatory network modeling to predict and simulate how cells transition between developmental states. Breakthrough validation: In zebrafish ...

Most of what scientists know about face development comes from studies in bony vertebrates such as mice, chickens, and zebrafish. However, their evolutionary counterparts, cartilaginous fishes, have ...

Craniofacial birth defects, including cleft lip and palate, are among the most common human congenital malformations. These craniofacial anomalies occur because of defects in neural crest cells, whose ...

An illustration of zebrafish heart development, showing the migration of cells in the growing embryo after 17 hours, 1 day and 2 days to form the heart. Most heart cells come from the embryonic ...

A crucial new mechanism that helps explain how the heart’s major blood vessels form during early development – and how disruptions to this process can lead to serious congenital heart defects – has ...

We have described the clinical manifestations of isotretinoin (ISO) neuroembryopathy (J Ped, 105, 595, 1984) and with others have suggested that disturbances in neural crest development may underlie ...