Kupffer cells are macrophages located in the liver that play a key role in liver pathology, concretely in metabolic dysfunction-associated steatotic liver disease (MASLD; formerly nonalcoholic fatty ...

The identification of Chitinase-3-like protein 1 (CHI3L1) as a crucial biomarker in liver disease is revolutionizing how clinicians approach the diagnosis, monitoring, and treatment of various liver ...

Study identifies chlorcyclizine as a potential treatment to reduce protoporphyrin-IX accumulation and liver damage in experimental models of EPP. Study: The histamine pathway is a target to treat ...

Hoth Therapeutics Inc. HOTH on Tuesday revealed preclinical data from its study on glial cell-derived neurotrophic factor ...

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis. MASH is a consequence of ...

By combining 3D human spheroids with AI-based digital pathology, researchers can better quantify fibrosis severity. The approach enhances drug response prediction and enables scalable, human-relevant ...

The Division of Gastroenterology and Hepatology at UAB offers a one-year intensive clinical Transplant Hepatology fellowship training program, providing outstanding clinical training preparing ...

A new study has found that MET (hepatocyte growth factor receptor) signaling plays a critical protective role in acetaminophen-induced acute liver failure (ALF). This pathway is shown to work as a ...