A new lipid nanoparticle platform delivers full-length antibodies inside cells, unlocking intracellular targets in cancer, ...
Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization and protein components of a lipid-transfer complex known as LPD-3.
A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune response. It can help scientists and engineers expand the use of RNA medicines ...
The formation of supramolecular polymers within living cells is an emerging strategy for regulating cellular functions, and ...
The formation of supramolecular polymers within living cells is an emerging strategy for regulating cellular functions, and ...
Interest in lipid nanoparticles (LNPs) as delivery vehicles for precision therapies in genetic diseases and cancers remains at an all-time high. Now, scientists from the University of Pennsylvania, ...
Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic diseases such as obesity and diabetes. In addition, it plays a critical role ...
An AI-identified lipid called P1 delivered mRNA 14.8 times more efficiently than the clinically approved lipid ALC-0315. Lipid P1's unique three-dimensional conformation allows it to bind ...
An international study by scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the ...
A detailed lipidomic comparison reveals that EPA and DHA are packaged very differently across marine sources, challenging the idea that all omega-3s are nutritionally equivalent. Study: Omega-3 Source ...