It is still not fully understood how, despite having the same set of genes, cells turn into neurons, bones, skin, heart, or roughly 200 other kinds of cells, and then exhibit stable cellular behavior ...

NIH funding has allowed scientists to see the DNA blueprints of human life—completely. In 2022, the Telomere-to-Telomere Consortium, a group of NIH-funded scientists from research institutions around ...

Electronic genome mapping (EGM) detects and validates structural variants in cancer genomes with improved accuracy over existing platforms, including optical mapping technologies PROVIDENCE, R.I., Oct ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose intimate folds govern the destiny of cells. A mapping of unprecedented precision ...

Today, genomics is saving countless lives and even entire species, thanks in large part to a commitment to collaborative and open science that the Human Genome Project helped promote. Twenty-five ...

Cold sore-causing HSV-1 doesn't just hijack cells it reconfigures the entire architecture of our DNA to aid its invasion. Researchers discovered that it actively reshapes the 3D structure of the human ...

J. Craig Venter, PhD, left, President Bill Clinton, and Francis S. Collins, MD, PhD, The White House, June 26, 2000. [Mark Wilson/Newsmakers/Getty Images] The announcement of the first draft of the ...

In a new study published in Nature Communications titled, “The reference genome of the human diploid cell line RPE-1,” researchers from University of Rome La Sapienza have produced the first reference ...

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.