Scientists have shown that small aggregates function as temporary RNA repositories, which are regulated by neural activity. LMU scientists have shown that small aggregates function as temporary RNA ...

Memories are thought to be stored in sparse groups of neurons called engrams. These are the cells that switch on during learning and can later switch on again during recall. In physiological aging and ...

The dentate gyrus (DG) is a region of the mammalian brain known to support the encoding of new memories. This brain region is part of the hippocampal formation, a set of brain regions involved in ...

Researchers have used advanced techniques to show that, in a key memory region of the brain called the hippocampus, immature, plastic neurons are present in significant numbers throughout the human ...

Mutations in the tau gene that cause frontotemporal dementia wreak all manner of neuronal havoc, from endolysosomal traffic jams to mitochondrial distress to a standstill in nucleocytoplasmic ...

As people age, their risk of developing neurodegenerative disorders like dementia, Alzheimer’s disease, and Parkinson’s disease increases. A new study from scientists at the University of California, ...

Under normal circumstances, tau protein is part of the brain’s infrastructure, important for stabilizing neurons into their proper shapes. But sometimes tau gets knotted up into tangles and turns ...

Spatial proteomics aims to reveal the locations of a group of proteins in cells or tissues to provide a spatial framework for the understanding of protein interactions or molecular mechanisms of ...

Under normal circumstances, tau protein is part of the brain’s infrastructure, important for stabilizing neurons into their proper shapes. But sometimes tau gets knotted up into tangles and turns ...

LMU scientists have shown that small aggregates function as temporary RNA repositories, which are regulated by neural activity. Cells constantly have to adapt the level of activity of certain genes to ...