New perspectives have been reached on the function of the Golgi apparatus. Scientists explain a basic difference between plant and animal cells. Cell biologists at the University of Heidelberg have ...

Disabling a part of brain cells that acts as a tap to regulate the flow of proteins has been shown to cause neurodegeneration, a new study from The University of Manchester has found. The research, ...

Inosine diphosphatase bound to Golgi membranes was studied in rice (Oryza sativa L. cv Nipponkai) cells. The enzyme was solubilized with Triton X-100 from isolated rice Golgi membranes and was highly ...

Alzheimer's disease (AD) progresses inside the brain in a rising storm of cellular chaos as deposits of the toxic protein, amyloid-beta (Aβ), overwhelm neurons. An apparent side effect of ...

A research team at the University of California, San Diego School of Medicine has provided a surprisingly simple explanation for the mechanism and features of the "Golgi apparatus" – a structure that ...

Recent studies have shown that under conditions of Golgi breakdown, Golgi glycosylation enzymes recycle to the endoplasmic reticulum (ER), whereas Golgi matrix proteins are retained in a set of ...

The Golgi apparatus has a central role in the trafficking and processing of membrane and secretory proteins in the exocytic and endocytic pathways, as well as in multiple recycling routes. It is ...

Brefeldin A (BFA), a fungal metabolite causing dysfunction of the Golgi apparatus in plant and animal cells, was used to investigate the role of secretory processes at the plasma membrane in ...

The Golgi apparatus modifies, sorts and packages proteins to be sent to their final destinations, whether that's within or outside of the cell. It's a core function, but little studied in the setting ...

Researchers have pinpointed a protein that keeps the trains running through the cell’s Grand Central station. The protein works in tandem with other molecules to pull membrane packets off the surface ...

Establishing the genetic basis of phenotypes such as skeletal dysplasia in model organisms can provide insights into biologic processes and their role in human disease. Affected mice had a nonsense ...

Prof. Fang-Jen S. Lee's team at National Taiwan University has discovered that an intermediate cellular metabolism molecule, glycerol, regulates the localization and function of the Golgi protein Imh1 ...