Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, progressive, multi-system, life-threatening disease, and diagnosing it early in the clinical course is essential for optimizing management ...

A novel, single tube, multi-parameter 7-color immunophenotyping assay was developed to characterize PNH clones in blood leukocytes. Monocytes, eosinophils and basophils had the highest proportion of ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disease in which the immune system breaks apart the red blood cells (RBCs) in the body. The medical term for this premature rupture of RBCs is ...

Ilene C. Wetiz, MD, professor of clinical medicine at the Keck School of Medicine at the University of Southern California, discusses the baseline characteristics of the case: "Our second case is how ...

Flow cytometry allows for the analysis of single cells in a population. This technique is analogous to microscopy, but instead of producing an image, a flow cytometer provides automated quantification ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disease in which changes in stem cells within the bone marrow prompt red blood cells to break apart. This deprives the body of the normal flow ...

Physicians report a case of delayed diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) leading to kidney failure with the need for hemodialysis. Undiagnosed PNH and other conditions involving ...

Flow cytometry is a way to look closely at the features of cells or particles. A sample of blood or tissue goes into a machine called a cytometer. In less than a minute, a computer can analyze ...

A phase II pilot study of valproic acid in relapsed/refractory chronic lymphocytic leukemia This is an ASCO Meeting Abstract from the 2009 ASCO Annual Meeting I. This abstract does not include a full ...

Around the same time, Mack Fulwyler, an engineer working at Los Alamos National Laboratory, needed to separate particles, so he drew on existing techniques to create droplets to separate cells from a ...