Using X-ray crystallography, researchers at Harvard Medical School, led by Stephen Harrison, determined the structure, at 4 Å resolution, of the un-bound simian immunodeficiency virus envelope ...
Seeing a glycoprotein on the envelope of the HIV virus snap open and shut in mere millionths of a second is giving investigators a new handle on the surface of the virus that could lead to broadly ...
In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.
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