A synthetic DNA binding compound has proved surprisingly effective at binding to the DNA of bacteria and killing all the bacteria it touched within two minutes. A synthetic DNA binding compound has ...

This week in science: What Jurassic Park got right about DNA in mosquito blood meals; a potential anti- cancer compound ...

In an effort to understand how colibactin, a compound produced by certain strains of E. coli, may be connected to the development of colorectal cancer, researchers are exploring how the compound ...

A simple tweak to a tool for making macrocyclic compounds could help increase the diversity of DNA-encoded libraries used by drug developers to rapidly screen and identify promising drug candidates ...

Many anticancer agents interfere with the polymerization step of DNA replication, but these drugs can be toxic to noncancerous cells. Italian researchers have now found a small-molecule kinase ...

Minor groove binding compounds represent a diverse class of small molecules that interact with the DNA double helix by inserting into its narrower, minor groove. This mode of binding affords a unique ...

People are occasionally exposed to potentially harmful substances in the environment or through their diets or habits. For example, a compound found in cigarette and industrial smoke, benzo(a)pyrene ...

TROY, N.Y. (NEWS10) — An antioxidant found in green tea may increase levels of p53, a natural anti-cancer protein, according to Rensselaer Polytechnic Institute (RPI). The p53 protein is also known as ...

DNA-encoded chemical library technologies are increasingly being adopted in drug discovery for hit and lead generation. DNA-encoded chemistry enables the exploration of chemical spaces four to five ...

According to subsection 4 of new §1(a) of the German Patent Act (GPA) implementing EU Directive 98/44/EC, a claim to a naturally occurring DNA sequence must recite the use of the DNA. There appears to ...