Ossification and concomitant vascularization are crucial processes for healing large bone fractures. Despite the multifunctional role of endothelial cells, vascularizing large bone grafts in ...

A new dual delivery system designed to sequentially release BMP2 and IGF1 in microparticles in an injectable hydrogel successfully healed an 8-mm cranial defect in rats. The study design and results ...

A recent project has revealed new bone formation in critical bone defects of an animal model with an exposure to a pencil-type non-thermal atmospheric-pressure plasma at surgery. Recent technological ...

A team of scientists headed by researchers at Technische Universität (TU) Dresden has used computer modeling and simulations to design novel bio-inspired molecules to enhance bone regeneration in mice ...

Step 1 represents acquiring a microtomographic image to be used as a mould to design the scaffold with graded porosity and three types of pores represented by number 2. The printing parameters were ...

Although autologous bone is the gold standard for filling bone defects, the additional morbidity involved for the patient in harvesting bone for grafting has led to a growing preference for ...

Defects of the skull and facial bones can pose difficult challenges for plastic and reconstructive surgeons. A synthetic material called hyperelastic bone -- readily produced by 3D-printing -- could ...

Effect of a chitosan sponge impregnated with platelet-derived growth factor on bone augmentation beyond the skeletal envelope in rat calvaria. Effect of basic fibroblast growth factor on angiogenesis ...

First described in 1942, Stafne bone defects (SBDs), are well-defined, radio-lucent lingual depressions of the lower jaw bone that are asymptomatic and most frequently diagnosed in middle-aged men.