The blood-brain barrier—a network of blood vessels and tissues that nurtures and protects the brain from harmful substances circulating in the blood—is disrupted in Alzheimer's disease. Now, ...

A new review paper was published in Aging titled "Peripheral vascular dysfunction and the aging brain." Aging is the greatest non-modifiable risk factor for most diseases, including cardiovascular ...

Using postmortem human brain tissue, three-dimensional imaging revealed vascular Aβ deposition patterns and a lower density of parenchymal amyloid plaques surrounding Aβ-positive vessels. Smooth ...

Vascular dementia is the second most common type of dementia. Strokes that affect cognitive (thinking) abilities cause vascular dementia. Vascular dementia often worsens in a stepwise pattern, and ...

Medical researchers conducted the largest-ever genome-wide association study of all-cause dementia, finding substantial genetic overlap with vascular dementia. In landmark research, scientists at The ...

“[...] the associations between common non-invasive measures of cardiovascular health (e.g., blood pressure) and risk of dementia are not well-established ...