Cancer does not develop overnight. It can take decades for cancer‐promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...

It sounds like a cyberpunk vision. Inspired by the generative abilities of AI, directed evolution, a biological system that works much like machine learning, can actually be used to improve proteins ...

Cancer does not develop overnight. It can take decades for cancer-promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...

A review examines the prevailing theory of cancer evolution. The authors highlight both practical and theoretical limitations of the clonal model of cancer evolution and propose areas for improving ...

Available in electronic full text to members of the University via the Library web catalogue. ELEC copy purchased with funds from the S. Dillon Ripley Endowment A fundamental and groundbreaking ...

New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. Germinal centers are high-speed evolution ...

In a study published in Developmental Cell, a team led by Prof. Robert K. Naumann from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences (CAS), and researchers from BGI ...

Billions of years of evolution have made modern cells incredibly complex. Inside cells are small compartments called organelles that perform specific functions essential for the cell’s survival and ...

Thought too hard to do, a new platform evolved proteins in mammalian cells, which could help researchers design drugs that work better in humans. “There are many, many examples, both published and ...

A new platform combines rational protein design with continuous evolution to discover functional molecules more efficiently. In medicine and biotechnology, the ability to evolve proteins with new or ...