The prefrontal cortex (PFC) is a crucial part of the mammalian brain, known to be involved in decision-making, planning, complex social behavior and integrating the activity of other brain regions.

Nearly every aspect of neuronal function depends on the accurate localization of polarized membrane proteins to the axon or dendrites. Selective sorting, selective transport and selective delivery are ...

Researchers from the research group Developmental Neurobiology at Ruhr-Universität Bochum around Professor Petra Wahle, in collaboration with partners from Mannheim and Jülich, Germany, and Linz, ...

Note: Some students might have trouble discussing this topic because they may have a family member with Alzheimer's disease. Model a nerve cell. Explain to students that the nervous system functions ...

Glycogen synthase kinase-3β (GSK-3β), governs axon and dendrite growth in determining cell polarity, according to research groups from China and Japan. GSK-3β is found throughout neurons but is less ...

Among all the bad things that can happen to the brain when it is severely jolted - in a car accident, for example - one of the most common and worrisome is axon damage. Axons are the long stalks that ...

Proteins go everywhere in the cell and do all sorts of work, but a fundamental question has eluded biologists: how do the proteins know where to go? A new study offers one answer. Proteins go ...

Two research groups in Asia have identified an enzyme that governs whether a neural projection becomes an axon or a dendrite and several of its upstream and downstream targets. Their findings on the ...