Tebipenem pivoxil hydrobromide is an orally bioavailable carbapenem with activity against uropathogenic Enterobacterales. Oral tebipenem pivoxil hydrobromide (HBr), a carbapenem, is as effective as ...
"The five factors with the highest odds of developing APN included obstructive and reflux uropathy, presentation to an acute care facility, urinary retention, history of UTI, and renal comorbidities.
A young male cadaveric kidney transplant developed delayed graft function. In addition to fever, serial allograft biopsies revealed progressive infiltration of polymorphonuclear leukocytes. After ...
intravenous antibiotics Cefepime-enmetazobactam may be more effective than piperacillin-tazobactam in treating complicated UTI and acute pyelonephritis caused by organisms that produce ...
GlaxoSmithKline (GSK) has resubmitted a new drug application (NDA) to the US Food and Drug Administration seeking approval of tebipenem pivoxil hydrobromide (HBr), an investigational oral carbapenem ...
Credit: Getty Images. The application includes data from the phase 3 ADAPT-PO trial, which evaluated the efficacy and safety of tebipenem HBr in 868 adults with cUTI or acute pyelonephritis. The Food ...