In contrast, parathyroidhormone (PTH) and parathyroidhormone-related protein (PTHrP) analogs belong to a different class of osteoporosis drugs called "anabolic" agents because they increase bone formation. There are fundamental differences in the mode of action of and skeletal response to PTH/PTHrP analogs compared with antiresorptive drugs [1].
Teriparatide has been used for patients with hypoparathyroidism.4-11 Natpara® (parathyroidhormone injection for subcutaneous use) is indicated as an adjunct to calcium and vitamin D to control hypocalcemia in patients with hypoparathyroidism.12 However, there is a recall of Natpara and teriparatide is one of two main alternatives recommended in a joint guidance statement from the American ...